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Scott Guelcher, PhD

Vanderbilt University

Associate Professor

Scott Guelcher, PhD


My current research is in the design, synthesis, and characterization of polymeric biomaterials for bone tissue engineering. Although autologous bone graft (vital tissue transplanted from one site in the patient to another) has the best capacity to stimulate healing of tissue defects, explantation both introduces additional surgery pain and also risks donor-site morbidity. One promising alternative to autograft is synthetic biomaterials that are designed to enhance healing through the natural tissue remodeling process. Polyurethanes comprise a class of synthetic polymers that are of fundamental interest to us because their mechanical and biological properties can be tuned to targeted values by controlling the structure.