To be considered for this award, nominees must have contributed to basic knowledge and understanding of the interaction of materials with biological molecules, cells, and/or tissues. Dr. West's passion as an innovator has been consistent over her career. From her work on photopolymerized hydrogels with cell adhesive and proteolytically degradable domains to the design of nanoparticles linked with protease sensitive peptides, clinical impact is a major focus. Her designer NO releasing hydrogels have shown great potential in graft endothelialization. Her pioneering work in nanotechnology offers both diagnostic imaging and therapeutic treatment for localized active tumor cells in normal tissue leading to truly significant advances in cancer management. This therapy is currently in three clinical trials for prostate tumors, lung tumors and recurrent head and neck tumors.