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Vaccine Delivery Vehicles

Wednesday, April 15, 2015 - 2:00pm to 4:00pm

Room 218 B/219 B

Vaccine Delivery Vehicles

Scope

Synthetic vaccines based on recombinant protein antigens or DNA-encoded antigens are a promising approach for combating infectious diseases, particularly in cases where whole pathogen vaccines are impracticable or unsafe. Synthetic vaccines based on tumor-associated antigens are also being pursued for cancer immunotherapy. The efficacy of protein and DNA vaccines can be greatly enhanced by the use of delivery vehicles that promote an antigen depot and/or uptake by antigen-presenting cells and co-deliver immunostimulatory adjuvant molecules such as cytokines or Toll-like receptor agonists. This session will explore the development of micro-/nanoparticles, emulsions, liposomes, and other biomaterial-based delivery vehicles that regulate the temporal and spatial presentation of vaccine antigens and adjuvant molecules in order to elicit a desirable immune response.

Oral Presentations