There is currently a vibrant discussion on the impact of our collective research enterprise. The implication of this debate has a profound effect on funding priorities, policies, public opinions, academic missions, health care delivery, and industry for years to come. The purpose of this debate is to provoke a thoughtful exchange of this important topic: Is translational research more impactful than basic science research? In this context, we will also explore how research impact is defined and whether the current drive towards translation harms the support of basic research. Can both co-exist and synergize? Several members of the International College of Fellows of Biomaterials Science and Engineering (ICF-BSE) will present different perspectives on this topic, helping the audience to gain a deeper perspective of the impact of translational versus basic research. The audience will be actively involved in the debate and will be polled before and after the debate to examine how the discussion has changed the opinion of the audience.